Thermo Fisher Scientific CD200 Monoclonal Antibody (325516), PE
인간 CD200 단백질을 인식하는 마우스 단클론 항체로, PE 형광 표지되어 유세포분석(Flow Cytometry)에 적합합니다. 단백질 A/G로 정제되었으며, 4°C 암소 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): 10 µL per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 325516 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human CD200 (Gln31–Gly232) |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | Buffered saline solution with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608820 |
Additional Formats
- Unconjugated: MA5-24048
- APC conjugated: MA5-23575
- Custom conjugation available on request
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant mouse CD200 is observed.
Target Information
CD200 is a type-1 membrane glycoprotein of the immunoglobulin superfamily containing two immunoglobulin domains. It is broadly expressed on cell surfaces and interacts with CD200R on myeloid cells, playing a role in inhibiting macrophage activation. Homologues exist in various herpesviruses and poxviruses. CD200 regulates myeloid cell activity and delivers inhibitory signals to macrophage lineages across tissues. Multiple alternatively spliced variants exist.
Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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