Thermo Fisher Scientific CD200 Monoclonal Antibody (325516), PE

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

10 µL per million cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

325516

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CD200 Gln31-Gly232 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD200,uniProtId:P41217-1,ncbiNodeId:9606,antigenRange:31-232,antigenLength:278,antigenImageFileName:MA5-23576_CD200_P41217-1_House_mouse.svg,antigenImageFileNamePDP:MA5-23576_CD200_P41217-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

PE PE PE

View additional formats

• Unconjugated
• APC
• Request custom conjugation

Excitation/Emission Max

565/576 nm View spectra

Form

Liquid

Purification

Protein A/G

Storage buffer

Buffered saline solution with BSA

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608820

Product Specific Information

In direct ELISAs, no cross-reactivity with recombinant mouse CD200 is observed.

Target Information

CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.