Thermo Fisher Scientific Phospho-EphA3 (Tyr596) Polyclonal Antibody
EPHA3 단백질의 Tyr596 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P) 실험에 적합하며, 인간, 마우스, 랫트 시료에 반응. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관.
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHA3 (Accession P29320), corresponding to amino acid residues around phosphorylated Tyr596. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816981 |
Product Specific Information
Antibody detects endogenous levels of EPHA3 only when phosphorylated at Tyr596.
Target Information
EPHA3 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA3 encodes a protein that binds ephrin-A ligands. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a cysteine-rich domain and two fibronectin type III repeats. Ephrin receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 binds ephrin-A ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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