Thermo Fisher Scientific Phospho-EphA2 (Tyr772) Polyclonal Antibody
Phospho-EphA2 (Tyr772) 폴리클로날 항체로, 인산화된 EphA2 단백질을 특이적으로 검출합니다. Western blot 및 IHC(파라핀 절편)에 사용 가능하며, 사람과 생쥐 시료에 반응합니다. 고순도 정제 항체로 연구용에 적합합니다.
- 카탈로그번호
- PA5105550
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHA2 (Accession P29317), corresponding to amino acid residues around phosphorylated Tyr772 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816978 |
Product Specific Information
This antibody detects endogenous levels of EPHA2 only when phosphorylated at Tyr772.
Target Information
EPHA2 belongs to the ephrin receptor subfamily of the protein tyrosine kinase (TK) family. EPH and EPH-related receptors are involved in developmental processes, particularly in the nervous system. EPHA2 is overexpressed in various human cancers. The TK group regulates cell-cell interactions such as differentiation, adhesion, motility, and death. Approximately 90 TK genes are known, including 58 receptor TKs (e.g., EGFR, EPH, FGFR, PDGFR, TRK, VEGFR) and 32 cytosolic TKs (e.g., ABL, FAK, JAK, SRC).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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