Thermo Fisher Scientific Phospho-EphA2 (Tyr594) Polyclonal Antibody
Phospho-EphA2 (Tyr594) 폴리클로날 항체로, 인산화된 EPHA2 단백질을 특이적으로 검출합니다. Western blot, IHC, ICC/IF에 최적화되어 있으며, 사람 및 생쥐 시료에 반응합니다. 고순도 정제 및 안정한 PBS/glycerol buffer로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHA2 (Accession P29317), corresponding to amino acid residues around phosphorylated Tyr594. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816977 |
Product Specific Information
This antibody detects endogenous levels of EPHA2 only when phosphorylated at Tyr594.
Target Information
EPHA2 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors are involved in developmental processes, especially in the nervous system. EPHA2 is overexpressed in many human cancers. The tyrosine kinase (TK) family regulates cell-cell interactions such as differentiation, adhesion, motility, and apoptosis. Approximately 90 TK genes have been sequenced, including 58 receptor TKs (e.g., EGFR, EPH, FGFR, PDGFR, TRK, VEGFR) and 32 cytosolic TKs (e.g., ABL, FAK, JAK, SRC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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