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Thermo Fisher Scientific Spectrin beta III (SPTBN2) Monoclonal Antibody (SPTBN2, 1583)
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Spectrin beta III(SPTBN2)에 특이적인 단일클론 항체로 Western blot, IHC, ICC, Flow cytometry 등에 사용 가능. 인간 시료에 반응하며, 비결합형 액상 형태로 제공. Glutamate 수송체 안정화 연구 및 신경퇴행 관련 연구에 적합.
- 카탈로그번호
- 6712-MSM3-P0
- 판매단위
- pk
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마지막 업데이트 2025. 08. 02. 오후 01:10
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Thermo Fisher Scientific 6712-MSM3-P0 Spectrin beta III (SPTBN2) Monoclonal Antibody (SPTBN2, 1583) 20 ug pk판매 단위 pk ·
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441,900원VAT 포함 486,090원
Thermo Fisher Scientific · Thermo Fisher Scientific Spectrin beta III (SPTBN2) Monoclonal Antibody (SPTBN2, 1583)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPTBN2, 1583 |
| Immunogen | Recombinant fragment (around aa356–475) of human SPTBN2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Spectrins are principal components of the cell membrane-cytoskeleton, composed of two alpha and two beta spectrin subunits.
The SPTBN2 gene encodes spectrin beta non-erythrocytic 2 (beta-III spectrin), which stabilizes the glutamate transporter EAAT4 at the plasma membrane surface.
Mutations in SPTBN2 cause spinocerebellar ataxia type 5 (SCA5), characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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