Thermo Fisher Scientific STING1/TMEM173 Recombinant Rabbit Monoclonal Antibody (STING1/8129R)
STING1/TMEM173 단백질을 인식하는 재조합 토끼 단일클론 항체. 인간 시료에 반응하며, IHC(P) 및 IHC(PFA) 실험에 적합. NF-κB 및 IRF3 신호 경로 연구에 활용 가능. 단백질 A/G로 정제된 액상 형태, 4°C 보관.
- 카탈로그번호
- 340061-RBM12-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific STING1/TMEM173 Recombinant Rabbit Monoclonal Antibody (STING1/8129R)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | STING1/8129R |
| Immunogen | Recombinant fragment (around aa190–290) of human TMEM173 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
STING (Stimulator of Interferon Genes) is a 379 amino acid signaling protein essential for innate immune responses. It activates NF-κB and IRF3 transcription pathways, inducing type I interferons (IFN-α and IFN-β) and promoting antiviral states. STING may function as a translocon involved in interferon induction and apoptotic signal transduction via MHC-II association. It helps detect intracellular viral RNA and B-form DNA and mediates death signaling through ERK pathway activation. STING is located in the endoplasmic reticulum, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed across tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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