Thermo Fisher Scientific COPS6 Monoclonal Antibody (OTI2F5), TrueMAB
COPS6 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western Blot 및 IHC(P) 실험에 적합. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 인간 유래 단백질(aa 58-327)을 면역원으로 사용. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F5 |
| Immunogen | Human recombinant protein fragment (aa 58–327 of human COPS6, produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
COPS6 is one of eight subunits of the COP9 signalosome, a conserved protein complex regulating multiple signaling pathways.
It functions similarly to the 19S regulatory particle of the 26S proteasome and interacts with SCF-type E3 ubiquitin ligases, acting as a positive regulator.
This protein belongs to the translation initiation factor 3 superfamily, involved in cell cycle regulation and may serve as a cofactor for HIV-1 accessory protein Vpr.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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