Thermo Fisher Scientific WNT10A Polyclonal Antibody
WNT10A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IHC(P) 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 20 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid synthetic peptide from near the carboxy terminus of human Wnt10a (amino acids 300–350). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152191 |
Product Specific Information
- Suggested positive control: RAW264.7 cell lysate
- Can be used with blocking peptide PEP-0662
- Predicted to not cross-react with Wnt10b
Target Information
The WNT gene family encodes secreted signaling proteins involved in oncogenesis and developmental processes such as regulation of cell fate and patterning during embryogenesis.
WNT10A is strongly expressed in promyelocytic leukemia and Burkitt’s lymphoma cell lines. It is coexpressed with WNT6 in colorectal cancer cell lines.
Overexpression may play key roles in carcinogenesis through activation of the WNT–β-catenin–TCF signaling pathway.
Both WNT10A and WNT6 genes are clustered in the chromosome 2q35 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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