Thermo Fisher Scientific SAPAP2 Polyclonal Antibody
SAPAP2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체. 신경 시냅스 단백질 연구용으로 적합.
- 카탈로그번호
- PA520541
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the center of human SAPAP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11156632 |
Product Specific Information
- Suggested positive control: L1210 cell lysate
- PA5-20541 can be used with blocking peptide PEP-0661
Target Information
SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family that specifically interacts with PSD-95/SAP90, a membrane-associated guanylate kinase localized at the postsynaptic density (PSD) in neuronal cells.
Like other SAPAP proteins, SAPAP2 acts as an adaptor protein interacting with various synaptic scaffolding proteins, cytoskeletal and signaling components such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2).
SAPAP2 mRNA is targeted to cell bodies similarly to SAPAP1 and SAPAP4, whereas SAPAP3 mRNA is mainly detected in cell bodies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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