Merck Anti-MYO1E antibody produced in rabbit

Anti-MYO1E antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies

Affinity isolated antibody, buffered aqueous glycerol solution

Synonyms

Anti-Myosin-Ie, Anti-Myosin-Ic

제품 설명

Myosin 1E (Myo1E), also known as myr-3 or human myosin-IC, belongs to the subclass-1 of the myosin-I family. It is encoded by a gene mapped to human chromosome 15q21.
Myosin 1E is a long-tailed protein ubiquitously expressed in vertebrates. Wild-type Myo1E protein is localized to the plasma membrane, while mutant Myo1E is expressed in the podocyte cytoplasm.
This single-headed, low molecular weight Myo1E protein consists of:

• Motor-head domain involved in binding ATP and F-actin
• Calmodulin-binding neck domain
• Tail domain that interacts with membranes and tail-binding proteins

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