Anti-Stage-Specific Embryonic Antigen-1 Antibody, clone MC-480
clone MC-480, Chemicon®, from mouse
SSEA-1, CD15, Lewis X, 3-FAL
SSEA-1 is expressed on the surface of early mouse embryos, murine embryonal carcinoma cells (EC), murine embryonic stem cells (ES) and murine & human germ cells (EG). No immunoreactivity is evident with undifferentiated human EC and ES cells. Expression of SSEA-1 is down regulated following differentiation of murine EC and ES cells. In contrast, the differentiation of human EC and ES cells is characterized by an increase in SSEA-1 expression.