Merck Anti-CRLF3 antibody produced in rabbit

Anti-CRLF3 antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

생물학적 소스

rabbit

Quality Level

100

결합

unconjugated

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

제품 라인

Prestige Antibodies® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

포장

antibody small pack of 25 μL

향상된 검증

RNAi knockdown
orthogonal RNAseq
Learn more about Antibody Enhanced Validation

technique(s)

immunoblotting: 0.04-0.4 μg/mL
immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:200-1:500

면역원 서열

IEHGVNTAEDLVREGEIAMLGGVGEENEKLWSFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGTVASRPPVQIEELIEKPGGIIVRWCKVDDDFTAQDYRLQFRKCTSNHFEDVYVGSE

UniProt 수납 번호

Q8IUI8

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... CRLF3(51379)

CRLF3 (cytokine receptor-like factor 3) gene is mapped to human chromosome 17q11.2 and is found to be frequently deleted in patients with Neurofibromatosis type 1 (NF1) microdeletions in the neurofibromin locus. It is also called as p48.2 based on its predicted molar mass and it encodes a 438aa intracellular protein. It contains a typical fibronectin type III (FNIII) domain. A palindromic Arg-Gly-Asp (RGD) repeat and a putative Trp-Ser-X-Trp-Ser (WSXWS) motif are located at the C-terminus of this domain. Its expression is found to be increased in lung cancer and leukemia cells. It is distributed in both cytoplasm and cell membrane in mammalian cells.