Merck VEGF164 from mouse

VEGF164 from mouse

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

VEGFA, VPF

생물학적 소스

mouse

재조합

expressed in HEK 293 cells

assay

≥95% (SDS-PAGE)

form

lyophilized

분자량

calculated mol wt 19.3 kDa (no tag)
observed mol wt 23-25 kDa (DTT-reduced. Protein migrates due to glycosylation. Ala 27 is the predicted N-terminal.)

포장

pkg of 10 μg

UniProt 수납 번호

Q00731

배송 상태

wet ice

저장 온도

−20°C

Gene Information

mouse ... VEGFA(22339)

Vascular endothelial growth factor A (VEGFA) is also known as Vascular permeability factor (VPF). VEGFA belongs to the PDGF/VEGF growth factor family. VEGFA is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. VEGFA is produced by a group of three major isoforms as a result of alternative splicing and if any three isoforms are produced (VEGFA120, VEGFA164, and VEGFA188) then this will not result in vessel defects and death of the full VEGFA knockout in mice.