Merck IL-2 R beta/CD122 human

IL-2 R beta/CD122 human

recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)

IL2RB, RP5-1170K4.6, P70-75

생물학적 소스

human

재조합

expressed in HEK 293 cells

태그

6-His tagged (C-terminus)

assay

≥90% (SDS-PAGE)

form

lyophilized

분자량

calculated mol wt 25.4 kDa
observed mol wt 40 kDa (DTT-reduced. Protein migrates due to glycosylation. Ala 27 is the predicted N-terminus.)

포장

pkg of 10 μg

불순물

<1 EU/μg endotoxin (LAL test)

UniProt 수납 번호

P14784

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... IL2RB(3560)

Interleukin-2 receptor (IL-2R)/ cluster of differentiation 122 (CD122) is a heterotrimeric protein, encoded by the gene mapped to human chromosome 22q12.3. The encoded protein is expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - α (CD25), β (CD122) and γ (CD132) - non-covalently associating. The α subunit is involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. IL2R β is a member of the type I cytokine receptor family.