TrueGel3D Hydrogel Kits
FAST-PVA, CD cell-degradable crosslinker
배송 상태
dry ice
저장 온도
−70°C
The gel is formed by stable thioether bonds between maleimide groups of PVA (FAST-PVA) and thiol groups on CD cell-degradable crosslinker. Malemide-functionalized PVA is specifically used to decrease the time for gel formation. The PVA polymer does not have cell attachment sites, but it can be customized to conjugate RGD peptide using TrueGel3D RGD peptide (TRUERGD-1EA) prior to the crosslinking step. The CD cell-degradable crosslinker is composed of matrix metalloprotease (MMP)-cleavable peptide (Pro-Leu-Gly-Leu-Trp-Ala), which allows cells to spread and migrate by secreting matrix metalloproteases (MMP1, MMP3, MMP7 and MMP9).
