Thermo Fisher Scientific HNF4A Monoclonal Antibody (H6939)
HNF4A 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체로, 인간·생쥐·랫트에 반응합니다. WB, IHC, ELISA, IP 등 다양한 응용에 사용 가능하며, 고순도 액상형 제품으로 냉장 보관 및 장기 보관 시 -20°C 저장이 권장됩니다.
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Thermo Fisher Scientific HNF4A Monoclonal Antibody (H6939)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10–20 µg/mL | - |
| ELISA | 3 µg/mL | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | H6939 |
| Immunogen | Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human HNF4-alpha (1–16 aa). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | Physiological saline |
| Contains | 0.1% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532198 |
Product Specific Information
This antibody specifically recognizes human HNF4 alpha 7–9 and cross-reacts with mouse and rat HNF4 alpha 7–9.
Target Information
Hepatocyte nuclear factor 4 alpha (HNF4α) is an orphan nuclear receptor expressed in the liver, kidney, intestine, and pancreas. Mutation of HNF4α in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4α gene is alternatively spliced and may generate up to nine different isoforms (HNF4α1–HNF4α9).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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