Thermo Fisher Scientific STUB1/CHIP Polyclonal Antibody
STUB1/CHIP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunoprecipitation에 적합하며, 비결합형 액상 형태로 제공. 4°C에서 보관하며, 수령 후 1년의 권장 사용기간을 가짐.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of Human STIP1 homology and U-box containing protein 1 (carboxy terminus of Hsp70-interacting protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The carboxyl terminus of hsc70-interacting protein (CHIP) interacts with both the constitutive form of hsc70 and the stress-inducible form, hsp70. This 35 kDa cytoplasmic protein is highly expressed in striated muscle and across a range of cultured tissues. CHIP directly binds to the carboxyl terminus of hsc70 and hsp70, decreasing ATPase activity and reducing overall chaperone efficiency. It also functions as an E3 ubiquitin ligase within the ubiquitin-proteasome system via its U-box domain, in conjunction with hsc70 and hsp90.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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