Thermo Fisher Scientific CABP7 Polyclonal Antibody
CABP7 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 생쥐, 랫트 반응성. WB 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로 CaBP7 신호전달 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the amino terminus of human CaBP7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152558 |
Product Specific Information
- Suggested positive control: HeLa cell lysate
- PA5-21001 can be used with blocking peptide PEP-1115.
Target Information
Calcium binding proteins (CaBP) play a crucial role in calcium-mediated cellular signal transduction in the central nervous system. The CaBP family shares similarity with calmodulin (CaM I) and can functionally substitute or augment CaM I activity.
CaBP7 (Calcium-binding protein 7) contains two EF-hand domains for calcium binding, sharing 70% homology with CaBP8 and 50% with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
CaBP7 and CaBP8 possess a unique targeting mechanism among CaBPs, contributing to differential Ca²⁺-sensing functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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