
Thermo Fisher Scientific CCDC106 Polyclonal Antibody
CCDC106 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot과 IHC에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체이며, PBS에 0.02% sodium azide 포함. p53의 음성 조절자로 알려진 CCDC106 연구에 적합.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the carboxy terminus of human CCDC106 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155777 |
Product Specific Information
- A suggested positive control is human brain tissue lysate.
- PA5-21003 can be used with blocking peptide PEP-1117.
Target Information
The coiled-coil domain is a common protein motif often involved in protein oligomerization and found in proteins such as transcription factors and intermediate filaments.
CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. It co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and promoting its degradation.
This suggests that CCDC106 functions as a negative regulator of p53.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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