Thermo Fisher Scientific Histone H2A Recombinant Rabbit Monoclonal Antibody (RM225)
Histone H2A 단백질을 특이적으로 인식하는 Thermo Fisher의 재조합 토끼 단일클론 항체입니다. Western blot, ICC/IF, ELISA, Luminex 등에 적합하며, 높은 특이성과 감도를 제공합니다. 동물 유래 성분이 없는 일관된 배치 품질을 보장합니다.
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- MA524662
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| ELISA | 0.2–1 µg/mL |
| Luminex (LUM) | 0.2–1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RM225 |
| Immunogen | Peptide corresponding to the C-terminus of human Histone H2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS (pH 7.2–7.4) with 50% glycerol, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2661885 |
Product Specific Information
This antibody reacts specifically with the Histone H2A protein, independent of post-translational modifications, with no cross-reactivity to other histone proteins.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
Histones are basic nuclear proteins responsible for nucleosome structure in eukaryotic chromosomal fibers. Two molecules of each core histone (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped, creating nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes, contributing to chromatin compaction.
This gene is intronless and encodes a member of the histone H4 family. Transcripts lack polyA tails and instead contain a palindromic termination element. It is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
- MA5-24662_Histone_H2A_P04908-1_Rabbit.svg
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- MA5-24662_Histone_H2A_P0C0S8-1_Rabbit_PDP.jpeg
- MA5-24662_Histone_H2A_Q96QV6-1_Rabbit.svg
- MA5-24662_Histone_H2A_Q96QV6-1_Rabbit_PDP.jpeg
- MA5-24662_Histone_H2A_P16104-1_Rabbit.svg
- MA5-24662_Histone_H2A_P16104-1_Rabbit_PDP.jpeg
- MA5-24662_Histone_H2A_P0C0S5-1_Rabbit.svg
- MA5-24662_Histone_H2A_P0C0S5-1_Rabbit_PDP.jpeg
- MA5-24662_Histone_H2A_P20671-1_Rabbit.svg
- MA5-24662_Histone_H2A_P20671-1_Rabbit_PDP.jpeg
- MA5-24662_Histone_H2A_Q96A08-1_Rabbit.svg
- MA5-24662_Histone_H2A_Q96A08-1_Rabbit_PDP.jpeg
- MA5-24662_Histone_H2A_Q96KK5-1_Rabbit.svg
- MA5-24662_Histone_H2A_Q96KK5-1_Rabbit_PDP.jpeg
- MA5-24662_Histone_H2A_Q99878-1_Rabbit.svg
- MA5-24662_Histone_H2A_Q99878-1_Rabbit_PDP.jpeg
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