Thermo Fisher Scientific 5HT3A R Polyclonal Antibody
Thermo Fisher Scientific의 5HT3A R Polyclonal Antibody는 마우스 5HT3A 수용체를 인식하는 토끼 유래 다클론 항체입니다. Western blot 및 IHC에 사용 가능하며, 합성 펩타이드를 면역원으로 제작되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 1st extracellular domain of mouse 5HT3A receptor conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide shares 86% identity with rat sequence.
- Specificity: 5HT3A receptor.
Target Information
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. It encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone functioning as a neurotransmitter, hormone, and mitogen.
This receptor mediates fast, depolarizing responses in neurons after activation. The heteromeric combination of A and B subunits is required for full receptor functionality, as individual subunits produce receptors with low conductance and response amplitude.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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