Thermo Fisher Scientific Human Caspase 7 Synthetic Peptide
Human Caspase 7의 C-말단 16개 아미노산 서열 기반 합성 펩타이드로, PA5-20114 항체의 블로킹 펩타이드로 사용 가능. 액상 형태, PBS 버퍼 내 0.1% BSA 포함. 연구용 시약으로 세포사멸 관련 단백질 연구에 적합.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human caspase-7.
PEP-0232 can be used as a blocking peptide with polyclonal antibody PA5-20114.
Target Information
Caspase 7 is part of a family of cysteine proteases divided into apoptotic and inflammatory subfamilies.
Unlike inflammatory caspases, apoptotic caspases are involved in cell death processes.
Executioner caspases, such as Caspase 7, are activated by initiator caspases and cleave cellular substrates leading to apoptosis.
Caspase 7 was identified based on homology with caspases 1 and 3, and the C. elegans cell death protein CED-3.
Alternative splicing of Caspase-7 mRNA results in three distinct isoforms.
Caspase-7 activity can be directly inhibited by XIAP expression.
Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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