Thermo Fisher Scientific Human Caspase 5 Synthetic Peptide
Human Caspase-5 중심부 14개 아미노산 서열 기반 합성 펩타이드로, PA5-20111 항체의 블로킹 펩타이드로 사용 가능. 액상 형태이며 농도 200 µg/mL, -20°C 보관, 드라이아이스 배송. 염증성 카스파아제 연구용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Dry ice |
Product Specific Information
This peptide corresponds to 14 amino acids near the center of human Caspase-5.
PEP-0229 can be used as a blocking peptide with polyclonal antibody PA5-20111.
Target Information
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with immune responses to microbial pathogens. Members include caspase-1, -4, -5, and -12. Activation of these caspases results in cleavage and activation of proinflammatory cytokines such as IL-1β and IL-18. Caspase-5 interacts with caspase-1, both being constituents of the NALP1 inflammasome, which triggers cleavage of pro-IL-1β. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-γ.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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