Thermo Fisher Scientific Human Caspase 7 Synthetic Peptide
인간 Caspase-7의 N-말단 16개 아미노산 서열 기반 합성 펩타이드. PA5-20115 항체의 블로킹 펩타이드로 사용 가능. 액상 형태, 200 µg/mL 농도, PBS(pH 7.2, 0.1% BSA) 저장용액. -20°C에서 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human caspase-7.
PEP-0233 can be used as a blocking peptide with polyclonal antibody PA5-20115.
Target Information
Caspase 7 is part of a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the inflammatory caspases, apoptotic caspases are involved in programmed cell death.
Executioner caspases, such as Caspase 7, are activated by initiator caspases and cleave cellular substrates leading to apoptosis.
Caspase 7 shares homology with caspases 1 and 3, and the C. elegans cell death protein CED-3.
Alternative splicing of Caspase-7 mRNA results in multiple transcript variants encoding distinct isoforms. Caspase-7 activity can be directly inhibited by XIAP expression.
Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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