Thermo Fisher Scientific CD19 Monoclonal Antibody (HIB19), Functional Grade, eBioscience
인간 CD19를 인식하는 HIB19 단클론 항체로, B세포 발현 분석 및 기능적 연구에 적합합니다. Flow cytometry 및 functional assay에 사용 가능하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 고순도(>90%)와 낮은 엔도톡신 수준(<0.001 ng/µg)을 보장합니다.
- 카탈로그번호
- 16-0199-xxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD19 Monoclonal Antibody (HIB19), Functional Grade, eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Flow Cytometry (Flow) | 1 µg/test | View 28 publications |
| Functional Assay (Functional) | Assay-Dependent | View publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Functional Grade, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HIB19 |
| Conjugate | Functional Grade |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
| RRID | AB_2865654 |
Available Conjugates
- Unconjugated
- Alexa Fluor 488, 532, 561, 660, 700
- APC, APC-eFluor 780
- Biotin
- Brilliant UV 395, 563, 615, 661, 737
- Brilliant Violet 480, 605, 650, 711
- eFluor 450, 506
- FITC
- NovaFluor Blue, Red, Violet, Yellow series
- PE, PE-Cyanine5, PE-Cyanine7, PE-eFluor 610
- PerCP-Cyanine5.5, PerCP-eFluor 710
- Super Bright 436, 600, 645, 702, 780
- Custom conjugation available upon request
Product Specific Information
The HIB19 monoclonal antibody reacts with human CD19, a 95 kDa transmembrane glycoprotein expressed on B cells throughout development except for terminally differentiated plasma cells. Follicular dendritic cells also express CD19. CD19 forms a multimolecular complex with CD21, CD81, Leu13, and MHC class II, associating with the B cell receptor (BCR). CD19 signaling induces tyrosine phosphorylation, calcium flux, and B cell proliferation. HIB19 and SJ25C1 recognize overlapping epitopes.
Applications Reported:
- Functional assays
- Flow cytometric analysis (fluorochrome-conjugated HIB19 recommended)
Applications Tested:
- Tested by flow cytometric analysis using normal human peripheral blood cells
- ≤1 µg per test (100 µL final volume, 10⁵–10⁸ cells/test)
- Titrate antibody for optimal performance
Storage and Handling:
- Use in a sterile environment
- 0.2 µm post-manufacturing filtered
Purity: >90% (SDS-PAGE)
Endotoxin Level: <0.001 ng/µg antibody (LAL assay)
Aggregation: <10% (HPLC)
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on all peripheral B cells and certain myeloid leukemia cells. CD19 acts as a signal-amplifying co-receptor for the B cell receptor (BCR), regulating proliferation and differentiation. It is a key regulator in both normal and malignant B cell activity. Mutations in CD19 can cause hypogammaglobulinemia, while overexpression leads to B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.