Thermo Fisher Scientific SCP2 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: HeLa, HCT116
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), resulting from transcription initiation from two independently regulated promoters.
The transcript from the proximal promoter encodes the longer SCPx protein, and the transcript from the distal promoter encodes the shorter SCP2 protein, with both sharing a common C-terminus.

Evidence suggests:

• SCPx is a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids.
• SCP2 functions as an intracellular lipid transfer protein.

This gene is highly expressed in organs involved in lipid metabolism and may play a role in Zellweger syndrome, where peroxisome deficiency impairs bile acid synthesis.
Alternative splicing produces multiple transcript variants encoding different isoforms.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.