Thermo Fisher Scientific ALDH1B1 Polyclonal Antibody
ALDH1B1 단백질을 검출하기 위한 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간 및 생쥐 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
- 카탈로그번호
- PA528554
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 226–517 of Human ALDH1B1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.87 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546030 |
Product Specific Information
- Recommended positive controls: A431
- Predicted reactivity: Mouse (94%), Rat (94%), Chimpanzee (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Aldehyde dehydrogenases (ALDHs) mediate NADP⁺-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation, and metabolism of corticosteroids, biogenic amines, and neurotransmitters.
Alcohol drinking habits and cardiovascular disease risk factors may be associated with ALDH gene variants.
ALDH1B1 (Aldehyde dehydrogenase family 1 member B1), also known as ALDH5 or ALDHX (Aldehyde dehydrogenase X, mitochondrial), is a 517 amino acid mitochondrial protein expressed in liver, testis, and to a lesser extent in brain.
ALDH1B1 belongs to the aldehyde dehydrogenase family and may play a major role in ethanol detoxification.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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