Thermo Fisher Scientific C16orf62 Polyclonal Antibody
C16orf62 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC 등 다양한 응용에 사용 가능. Human 및 Mouse 반응성 확인. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용.
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- PA528553
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Thermo Fisher Scientific C16orf62 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 3 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunocytochemistry (ICC/IF) | – | View 3 publications |
| Immunoprecipitation (IP) | – | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 1–228 of Human C16orf62 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546029 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLaS3, Molt-4, Raji
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Acts as a component of the retriever complex, a heterotrimeric complex related to the retromer cargo-selective complex (CSC). It is essential for retromer-independent retrieval and recycling of cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The retriever complex recruitment to endosomal membranes involves CCC and WASH complexes. It drives retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, maintaining numerous cell surface proteins involved in migration, adhesion, nutrient supply, and signaling. Also involved in copper-dependent ATP7A trafficking between the trans-Golgi network and peripheral vesicles. Not required for CCC complex stability. [UniProt]
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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