Thermo Fisher Scientific KV1.1 (KCNA1) (extracellular) Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Product is shipped at room temperature as a lyophilized powder.
• Store at -20 °C upon receipt.
• Reconstitution: add 50 µL of deionized water.

Target Information

This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel.
The encoded protein has six putative transmembrane segments, with the loop between S5 and S6 forming the pore and containing the conserved selectivity filter motif.
The functional channel is a homotetramer.

• The N-terminus associates with beta subunits that can modify inactivation properties and expression levels.
• The C-terminus interacts with PDZ domain proteins responsible for channel targeting.
  Mutations in this gene have been associated with myokymia with periodic ataxia.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.