Thermo Fisher Scientific KCNQ5 Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitute using 50 µL deionized water.

Target Information

KCNQs are members of the voltage-dependent non-inactivating potassium channel family. There are five known KCNQs (KCNQ1–5) found in the central nervous system.
KCNQ3 and KCNQ5 form heteromultimers that substantially increase the M-current, which controls neuron excitability and responsiveness to synaptic inputs.
Genetic mutations in these proteins are linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain, and epilepsy.
Voltage-dependent potassium channels regulate the resting membrane potential and modulate the excitability of electrically active cells. These channels are typically tetrameric and can interact with auxiliary subunits that modify channel currents.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.