Thermo Fisher Scientific KCNQ5 Polyclonal Antibody
Rabbit 폴리클로날 항체로 KCNQ5 단백질을 검출. Western blot, IHC, ICC/IF에 사용 가능. Lyophilized 형태로 제공되며 -20°C 보관. 신경세포 흥분성과 M-current 연구에 적합.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)RGSQDFYPKWRESK, corresponding to amino acid residues 856–869 of mouse Kv7.5 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736022 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitute using 50 µL deionized water.
Target Information
KCNQs are members of the voltage-dependent non-inactivating potassium channel family. There are five known KCNQs (KCNQ1–5) found in the central nervous system.
KCNQ3 and KCNQ5 form heteromultimers that substantially increase the M-current, which controls neuron excitability and responsiveness to synaptic inputs.
Genetic mutations in these proteins are linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain, and epilepsy.
Voltage-dependent potassium channels regulate the resting membrane potential and modulate the excitability of electrically active cells. These channels are typically tetrameric and can interact with auxiliary subunits that modify channel currents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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