Thermo Fisher Scientific TSC22D1 Monoclonal Antibody (OTI4A11), TrueMAB
TSC22D1 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot과 IHC(P)에서 검증됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 세포 성장, 분화, 사멸 조절 연구에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A11 |
| Immunogen | Full length human recombinant protein of human TSC22D1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TSC22 domain family protein (TSC22) is a transcription factor belonging to the TSC-22/Dip/Bun family of early response genes.
It acts as a transcriptional repressor on the C-type natriuretic peptide (CNP) promoter and is involved in regulating cell growth, differentiation, and apoptosis.
TSC22D1 modulates the transcriptional activity of Smad3 and Smad4 and is expressed ubiquitously in fetal and adult tissues, including aortic endothelial cells.
Expression is induced by cytokines such as TGFB, and TSC22 proteins may serve as potential therapeutic targets in leukemia and prostate cancer research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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