Thermo Fisher Scientific TSC22D1 Monoclonal Antibody (OTI4H8), TrueMAB
TSC22D1 단백질을 인식하는 Mouse monoclonal antibody (OTI4H8)로, WB, IHC(P), Flow Cytometry에 적합합니다. Human 시료에 반응하며, Lyophilized 형태로 제공됩니다. 연구용으로 세포 성장, 분화, 사멸 관련 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H8 |
| Immunogen | Full length human recombinant protein of human TSC22D1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve an antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TSC22 domain family protein (TSC22) is a transcription factor belonging to the large family of early response genes. It acts as a transcriptional repressor on the C-type natriuretic peptide (CNP) promoter. TSC22 is part of the TSC-22/Dip/Bun family and is found in both cytoplasm and nucleus.
This protein regulates cell growth, differentiation, and apoptosis, and modulates the transcriptional activity of Smad3 and Smad4. It is ubiquitously expressed in most tissues, including fetal and adult, and induced by cytokines such as TGFB.
TSC22 proteins are potential therapeutic targets in leukemia and prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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