Thermo Fisher Scientific CD16 Monoclonal Antibody (eBioCB16 (CB16)), Brilliant Ultra Violet 737, eBioscience
인간 CD16(FcγRIII) 인식을 위한 eBioCB16 단클론 항체로, Brilliant Ultra Violet 737 형광체 결합. 유세포분석용으로 검증되어 있으며, 5 µL/test 사용 권장. 광민감성이 있으므로 암조건에서 보관 필요. 연구용으로만 사용 가능.
- 카탈로그번호
- 367-0168-4x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD16 Monoclonal Antibody (eBioCB16 (CB16)), Brilliant Ultra Violet 737, eBioscience
Thermo Fisher Scientific CD16 Monoclonal Antibody (eBioCB16 (CB16)), Brilliant Ultra Violet 737, eBioscience
Applications and Tested Dilution
- Application: Flow Cytometry
- Tested Dilution: 5 µL (0.125 µg)/test
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Brilliant Ultra Violet™ 737 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | eBioCB16 (CB16) |
| Conjugate | Brilliant Ultra Violet™ 737 |
| Excitation / Emission Max | 350 / 740 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2895942 |
Available Formats
- Unconjugated
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 661
- Brilliant UV 805
- Brilliant Violet 480
- eFluor 450
- eFluor 506
- FITC
- Functional Grade
- NovaFluor Blue 610-70S
- NovaFluor Blue 660-120S
- NovaFluor Red 710
- NovaFluor Red 725
- NovaFluor Yellow 660
- NovaFluor Yellow 730
- PE
- PE-Cyanine5
- PE-Cyanine7
- PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 600
- Super Bright 645
- Super Bright 702
- Super Bright 780
- Request custom conjugation
Product Specific Information
The eBioCB16 monoclonal antibody recognizes CD16 (Fc gammaRIII), a low-affinity receptor for IgG (50–80 kDa).
CD16 includes two genes: CD16A (FcγRIIIA) expressed in macrophages and NK cells, and CD16B (FcγRIIIB) expressed in neutrophils.
Two polymorphisms, NA-1 and NA-2, affect phagocytic capacity. CD16 binds IgG immune complexes (preferentially IgG1 and IgG3) and mediates ADCC, phagocytosis, and degranulation.
Applications Reported: Flow cytometric analysis.
Applications Tested: Pre-diluted and tested on human peripheral blood cells (5 µL/test).
Fluorochrome Information:
Brilliant Ultra Violet™ 737 (BUV737) emits at 732 nm, excitable by 355 nm UV laser. Ensure instrument compatibility.
Staining Recommendations:
Use Super Bright Complete Staining Buffer (Product # SB-4401) or Brilliant Stain Buffer (Product # 00-4409) to minimize non-specific polymer interactions.
Light Sensitivity:
Protect vial and stained samples from light.
Fixation:
Samples can be stored up to 3 days at 4°C in IC Fixation Buffer (Product # 00-8222) or 1-step Fix/Lyse Solution (Product # 00-5333).
Compatible with short-term methanol fixation (<1 hour).
Excitation: 355 nm
Emission: 732 nm
Laser: Ultraviolet Laser
BRILLIANT ULTRA VIOLET™ is a trademark of Becton, Dickinson and Company, used under license. Powered by Sirigen™.
Target Information
CD16 encodes an Fc receptor for IgG involved in immune complex clearance, ADCC, and viral infection enhancement.
The gene FCGR3A (chromosome 1) is expressed in NK cells, while FCGR3B is expressed in neutrophils.
Mutations are linked to immunodeficiency 20, lupus, and neonatal neutropenia.
Alternative splicing produces multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.