Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI3B11), TrueMAB

Applications

• Western Blot (WB): 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The protein encoded by PTPRE belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Two alternatively spliced transcript variants have been reported:

• Receptor-type PTP: Contains a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains.
• Nonreceptor-type PTP: Contains a distinct hydrophilic N-terminus.

Studies in mice suggest regulatory roles in RAS-related signal transduction, cytokine-induced STAT signaling, and activation of voltage-gated K⁺ channels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.