Thermo Fisher Scientific eIF3a Polyclonal Antibody
eIF3a 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, Human과 Mouse 시료에 반응합니다. Affinity Chromatography로 정제된 액상 항체로, -20°C에서 보관합니다.
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- PA587456
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–250 of human EIF3A (NP_003741.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.68 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804164 |
Product Specific Information
- Immunogen sequence:
MPAYFQRPEN ALKRANEFLE VGKKQPALDV LYDVMKSKKH RTWQKIHEPI MLKYLELCVD LRKSHLAKEG LYQYKNICQQ VNIKSLEDVV RAYLKMAEEK TEAAKEESQQ MVLDIEDLDN IQTPESVLLS AVSGEDTQDR TDRLLLTPWV KFLWESYRQC LDLLRNNSRV ERLYHDIAQQ AFKFCLQYTR KAEFRKLCDN LRMHLSQIQR HHNQSTAINL NNPESQSMHL ETRLVQLDSA ISMELWQEAF - Positive Samples: HepG2, Jurkat, Mouse heart, Mouse ovary
- Cellular Location: Cytoplasm
Target Information
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, required for multiple steps in initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates recruitment of initiation factors to form the 43S pre-initiation complex. It also participates in mRNA recruitment, scanning for AUG recognition, and recycling of post-termination ribosomal complexes. The eIF-3 complex selectively regulates translation of mRNAs involved in cell proliferation, differentiation, and apoptosis.
[UniProt Reference]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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