Thermo Fisher Scientific MYPT1 Polyclonal Antibody
MYPT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합. Human, Mouse, Rat 시료 반응성. 고순도 Affinity Chromatography 정제 및 안정적 PBS/glycerol 저장.
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Thermo Fisher Scientific MYPT1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–200 of human PPP1R12A (NP_0024711) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.27 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804167 |
Product Specific Information
Immunogen sequence:
MKMADAKQKR NEQLKRWIGS ETDLEPPVVK RQKTKVKFDD GAVFLAACSS GDTDEVLKLL HRGADINYAN VDGLTALHQA CIDDNVDMVK FLVENGANIN QPDNEGWIPL HAAASCGYLD IAEFLIGQGA HVGAVNSEGD TPLDIAEEEA MEELLQNEVN RQGVDIEAAR KEEERIMLRD ARQWLNSGHI NDVRHAKSGG
Positive Samples: U-87MG, LO2, Jurkat, HeLa
Cellular Location: Cytoplasm
Target Information
Myosin phosphatase target subunit 1 (MYPT1), also known as the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. This enzyme regulates actin–myosin interactions downstream of the small GTPase Rho. RhoA activates Rho-kinase, which phosphorylates and inactivates myosin phosphatase, leading to increased myosin light chain (MLC) phosphorylation and contractility. Multiple transcript variants encoding distinct isoforms are known for this gene.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-87459_MYPT1_O14974-1_Rabbit.svg, PA5-87459_MYPT1_O14974-1_Rabbit_PDP.jpeg)
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