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Thermo Fisher Scientific RIC8A Monoclonal Antibody (OTI3G3), TrueMAB
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Thermo Fisher Scientific RIC8A Monoclonal Antibody (OTI3G3), TrueMAB

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RIC8A 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공되며 연구용으로 사용됩니다.

카탈로그번호
CF501055
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오후 01:28
Thermo Fisher Scientific CF501055 RIC8A Monoclonal Antibody (OTI3G3), TrueMAB 100 ug pk판매 단위 pk ·
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784,000원VAT 포함 862,400원

Thermo Fisher Scientific · Thermo Fisher Scientific RIC8A Monoclonal Antibody (OTI3G3), TrueMAB

Thermo Fisher Scientific RIC8A Monoclonal Antibody (OTI3G3), TrueMAB

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:1,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:50
Immunocytochemistry (ICC/IF) 1:100

Product Specifications

Specification Description
Species Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone OTI3G3
Immunogen Full length human recombinant protein of human RIC8A produced in HEK293T cell
Conjugate Unconjugated
Form Lyophilized
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS, pH 7.3, with 8% trehalose
Contains No preservative
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

RIC8A is a guanine nucleotide exchange factor (GEF) that activates specific G-alpha proteins such as GNAI1, GNAO1, and GNAQ, but not GNAS.
It regulates microtubule pulling forces during mitosis by stimulating G(i)-alpha protein activity, influencing the release of G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex.
It also enhances G(q)-coupled receptor-mediated ERK activation via GNAQ.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.

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