
Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI3C4), TrueMAB
Human LIPG 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot, IHC, ICC/IF, IP에 사용 가능. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공되며 보존제가 없음. 연구용으로 HDL 대사 및 지방분해 관련 연구에 적합.
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Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI3C4), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C4 |
| Immunogen | Full length human recombinant protein of human LIPG produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions locally to modulate lipoprotein metabolism. Overexpression of LIPG reduces HDL cholesterol levels, while deficiency increases them.
LIPG exhibits phospholipase activity and plays roles in lipoprotein metabolism and vascular biology. It is classified within the triglyceride lipase family, possessing a lid region that confers substrate specificity. As a carboxyl esterase, LIPG hydrolyzes high-density lipoproteins, emulsifies triglycerides, and contributes to dietary fat digestion through heparin binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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