Thermo Fisher Scientific Caffeine Monoclonal Antibody (F1-P2B1G1)
Caffeine을 표적으로 하는 Mouse IgG2b 단일클론 항체로 ELISA, IP, RIA 분석에 적합. Unconjugated 형태이며 1 mg/mL 농도. Ion-exchange chromatography로 정제됨. 연구용으로만 사용 가능.
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Applications
ELISA (ELISA)
- Assay-dependent
Immunoprecipitation (IP)
- Assay-dependent
Radioimmune Assays (RIA)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F1-P2B1G1 |
| Immunogen | Caffeine-3-KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage buffer | PBS, pH 7.4, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 6 months. For long-term storage store at –20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982727 |
Product Specific Information
MA5-14725 targets caffeine in ELISA, IP, and RIA applications and shows reactivity with chemical samples.
The MA5-14725 immunogen is caffeine-3-KLH.
Product MA514725 is a smaller package size of MIC0401 (formerly sold as a Seradyn product).
Target Information
Caffeine is a methylxanthine alkaloid found in the seeds, nuts, or leaves of a number of plants native to South America and East Asia. It is structurally related to adenosine and acts primarily as an adenosine receptor antagonist with psychotropic and anti-inflammatory activities.
Upon ingestion, caffeine binds to adenosine receptors in the central nervous system (CNS), inhibiting adenosine binding. This prevents adenosine-mediated downregulation of CNS activity, thereby stimulating the medullary, vagal, vasomotor, and respiratory centers.
Caffeine also promotes neurotransmitter release that further stimulates CNS activity. Its anti-inflammatory effects are due to nonselective competitive inhibition of phosphodiesterases (PDEs), which raises intracellular cyclic AMP (cAMP) levels, activates protein kinase A, and inhibits leukotriene synthesis, leading to reduced inflammation and innate immunity.
Source: National Center for Biotechnology Information. PubChem Compound Database; CID=2519.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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