Thermo Fisher Scientific Ferritin Monoclonal Antibody (523)
인간 Ferritin을 검출하는 Mouse IgG1 단일클론 항체로 ELISA, IP, IF, RIA에 사용 가능. Human liver ferritin을 면역원으로 제작되었으며, 19kDa Ferritin 단백질에 반응. 단백질 A 정제, 액상 형태, 2-8°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
| Radioimmune Assays (RIA) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 523 |
| Immunogen | Human liver ferritin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Refrigerated at 2–8°C for up to 6 months; for long-term storage, store at –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979575 |
Product Specific Information
MA5-14735 detects Ferritin in ELISA, IP, IF, and RIA applications and shows reactivity to human samples.
The immunogen is human liver ferritin, and the antibody detects ferritin with a predicted molecular weight of approximately 19 kDa.
Product MA514735 is a smaller package size of MIF2503 (formerly sold as a Seradyn product).
Target Information
Ferritin is the major intracellular iron storage protein found in both prokaryotes and eukaryotes. It comprises 24 subunits of heavy (H) and light (L) chains.
Variation in subunit composition may affect iron uptake and release rates in different tissues.
Ferritin stores iron in a soluble, nontoxic form, playing a crucial role in iron homeostasis.
Defects in the light chain ferritin gene are associated with neurodegenerative diseases and hyperferritinemia-cataract syndrome.
The ferritin holoenzyme has a molecular weight of about 450 kDa and can store up to 4,500 atoms of ferric iron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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