Thermo Fisher Scientific Insulin (beta-Cell and Insulinoma Marker) Monoclonal Antibody (SPM531)
Thermo Fisher Scientific의 Insulin Monoclonal Antibody (SPM531)는 베타세포 및 인슐린종 마커로 사용됩니다. IHC, ICC, Flow Cytometry 등 다양한 응용 가능. Mouse IgG1, kappa 항체이며 Protein A/G로 정제된 액상 형태. 연구용으로만 사용.
- 카탈로그번호
- 3630MSM2XP1ABX
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Pig, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM531 |
| Immunogen | Full length (1–84 amino acid) purified pig insulin, conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It promotes glycogen storage, triglyceride formation, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide produced from a precursor peptide, proinsulin, which is post-translationally cleaved into two chains (peptide A and peptide B) covalently linked via two disulfide bonds and one molecule of C-peptide.
Insulin deficiency results in diabetes mellitus, a major cause of morbidity and mortality. Insulin is also present in tumors of beta-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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