Thermo Fisher Scientific EML1 Polyclonal Antibody
Thermo Fisher Scientific의 EML1 Polyclonal Antibody는 인간, 마우스, 랫트 등 다양한 종에 반응하는 항체로, Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View 1 publication |
| Immunoprecipitation (IP) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 753–815 of EML1 (Uniprot ID: O00423) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153100 |
Product Specific Information
- Recommended positive controls: H1299, NIH-3T3
- Predicted reactivity: Mouse (100%), Rat (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Human echinoderm microtubule-associated protein-like 1 (EML1) is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are genetic disorders characterized by congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on genetic type.
USHs are categorized as:
- Type I (USH1A–USH1F): most severe form
- Type II (USH2A, USH2B)
- Type III (USH3)
Two transcript variants encoding different isoforms have been identified for this gene.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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