Thermo Fisher Scientific UBE2L6 Polyclonal Antibody
Rabbit polyclonal antibody targeting human UBE2L6 for WB, IHC, and ICC applications. High specificity with recombinant UBE2L6 immunogen. Supplied as liquid, unconjugated form at 0.1 mg/mL. Ideal for protein ubiquitination research.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UBE2L6. Recombinant protein control fragment (Product #RP-102070). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649182 |
Product Specific Information
Immunogen sequence:
NLSSDDANVL VWHALLLPDQ PPYHLKAFNL RISFPPEYPF KPPMIKFTTK IYHPNVDENG QICLPIISSE NWKPCTKTCQ VLEALNVLVN RPNIREPLRM DLADLLTQNP ELFRKNAEEF TLR
Highest antigen sequence identity to the following orthologs:
- Mouse: 76%
- Rat: 74%
Target Information
The modification of proteins with ubiquitin is an essential mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s).
UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family and functions in the E6/E6-AP-induced ubiquitination of p53.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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