Thermo Fisher Scientific UBE2L6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human UBE2L6. Recombinant protein control fragment (Product #RP-102070). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UBE2L6,uniProtId:O14933-1,ncbiNodeId:9606,antigenRange:24-146,antigenLength:153,antigenImageFileName:PA5-51895_UBE2L6_O14933-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51895_UBE2L6_O14933-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649182

Product Specific Information

Immunogen sequence: NLSSDDANVL VWHALLLPDQ PPYHLKAFNL RISFPPEYPF KPPMIKFTTK IYHPNVDENG QICLPIISSE NWKPCTKTCQ VLEALNVLVN RPNIREPLRM DLADLLTQNP ELFRKNAEEF TLR

Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 74%.

Target Information

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.