Thermo Fisher Scientific UBE2E3 Polyclonal Antibody
Human UBE2E3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공. 단백질 유비퀴틴화 연구 및 세포 성장 조절 관련 연구에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific UBE2E3 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UBE2E3. Recombinant protein control fragment (Product #RP-102079). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649177 |
Product Specific Information
Immunogen sequence:
SSDRQRSDDE SPSTSSGSSD ADQRDPAAPE PEEQEERKPS ATQQKKNTKL SSKTTAKLST SAKRIQKELA EITLDPPPNC SAGPKGDNIY EWRSTILGPP GSVYEGGVFF LDITFSSDYP FKPPKVTFRT RIYHCNINSQ GV
Ortholog sequence identity:
- Mouse: 100%
- Rat: 87%
Target Information
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates.
- Activation (E1 enzyme): ATP-dependent activation of the Ub C-terminus and assembly of multi-Ub chains.
- Conjugation (E2 enzyme): Ub-conjugating enzyme (E2) generates an intermediate Ub-E2 complex.
- Ligation (E3 enzyme): Ub-ligase (E3) catalyzes the transfer of Ub from E2 to the target protein substrate.
UBE2E3 (also known as UBCH9) catalyzes the covalent attachment of ubiquitin to other proteins and regulates transepithelial sodium transport in renal cells. It may also play a role in cell growth arrest. The UBE2E3 protein shuttles between the cytoplasm and nucleus in an IPO11-dependent manner and is ubiquitously expressed at low levels, with high expression in skeletal muscle.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.