Thermo Fisher Scientific MAGEA10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MAGEA10. Recombinant protein control fragment (Product #RP-92198). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MAGEA10,uniProtId:P43363-1,ncbiNodeId:9606,antigenRange:44-150,antigenLength:369,antigenImageFileName:PA5-51897_MAGEA10_P43363-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51897_MAGEA10_P43363-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643674

Product Specific Information

Immunogen sequence: TSSSFPSSFP SSSSSSSSSC YPLIPSTPEE VSADDETPNP PQSAQIACSS PSVVASLPLD QSDEGSSSQK EESPSTLQVL PDSESLPRSE IDEKVTDLVQ FLLFKYQ

Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 37%.

Target Information

MAGEA10 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.