Thermo Fisher Scientific Phospho-MBP (Tyr203) Polyclonal Antibody
인간 MBP Tyr203 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Dot blot 등 연구용에 적합합니다. KLH 결합 합성 인산화 펩타이드로 면역화되었으며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. 단백질 A 및 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications
- Dot blot (DB)
Tested Dilution
- 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y203 of human MBP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2140489 |
Target Information
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. MBP-related transcripts are also present in the bone marrow and immune system, arising from the long MBP gene (“Golli-MBP”). This gene contains additional upstream exons and undergoes alternative splicing to produce two sets of MBP-related transcripts:
- Golli-MBP transcripts – contain unique Golli exons spliced in-frame with MBP exons, encoding hybrid proteins with N-terminal Golli and MBP sequences.
- Classic MBP transcripts – contain only MBP exons, producing well-characterized myelin basic proteins.
This conserved gene structure indicates that MBP and Golli transcription units are functionally and regulatory interlinked.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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