Thermo Fisher Scientific CIS Recombinant Rabbit Monoclonal Antibody (5H6L11)
Thermo Fisher Scientific의 CIS Recombinant Rabbit Monoclonal Antibody (Clone 5H6L11)은 인간 CISH 단백질을 타깃으로 하는 고특이성 항체로, WB 및 ICC/IF에 사용 가능. 재조합 기술로 생산되어 로트 간 일관성과 높은 감도를 제공하며, 다양한 종에 반응 예측됨. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5H6L11 |
| Immunogen | Protein corresponding to Human CISH (aa 1–258) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2577015 |
Product Specific Information
This antibody is predicted to react with Monkey, Feline, Rabbit, Rat, Mouse, and Goat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to large rabbit immune repertoire
Target Information
CIS contains SH2 and SOCS box domains and belongs to the cytokine-induced STAT inhibitor (CIS) protein family, also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI). CIS family members act as cytokine-inducible negative regulators of cytokine signaling. Expression of this gene can be induced by IL2, IL3, GM-CSF, and EPO in hematopoietic cells. Proteasome-mediated degradation of CIS is involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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