Thermo Fisher Scientific HSPA4 Polyclonal Antibody
HSPA4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트, 영장류 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human HSPA4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 176 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979480 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The HSP 70 family is composed of four highly conserved proteins: HSP 70, HSC 70, GRP 75, and GRP 78.
HSP 70 expression is strongly induced in response to heat stress.
HSP 70 and HSC 70 play key roles in the cytosolic, endoplasmic reticulum, and mitochondrial import machinery and are found in both the cytosol and nucleus of mammalian cells.
GRP 78 is localized in the endoplasmic reticulum, where it assists in folding and translocation of nascent peptide chains.
GRP 75 is expressed in the mitochondrial matrix and aids in the folding and translocation of polypeptides of nuclear and mitochondrial origin.
Members of the HSP 70 family are believed to act as force-generating motors, utilizing ATP hydrolysis for their activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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