Thermo Fisher Scientific Caspase 3 Recombinant Rabbit Monoclonal Antibody (SR03-01)
Caspase-3 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, Protein A로 정제되어 높은 특이성과 재현성을 제공합니다.
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카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Caspase 3 Recombinant Rabbit Monoclonal Antibody (SR03-01)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:20–1:50 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SR03-01 |
| Immunogen | Synthetic peptide within human Caspase-3 (aa 60–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931493 |
Target Information
This gene encodes a protein that belongs to the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits (large and small) that dimerize to form the active enzyme. Caspase-3 cleaves and activates caspases 6, 7, and 9, and is itself processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, associated with neuronal death in Alzheimer’s disease. Alternative splicing of this gene results in two transcript variants encoding the same protein.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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