Thermo Fisher Scientific Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Monoclonal Antibody (LH2)
Cytokeratin 10(KRT10)을 인식하는 마우스 단클론 항체로, 상피세포의 suprabasal 층 마커로 사용됩니다. Western blot 및 면역조직화학(IHC) 등 다양한 응용에 적합합니다. Protein A/G로 정제된 액상 형태이며, PBS(pH 7.4)에 보존제 없이 제공됩니다.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LH2 |
| Immunogen | Skin extract of a human Psoriasis patient |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, present in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). Although not typically endothelial markers, cytokeratins have been found in some microvascular endothelial cells.
At least 20 different cytokeratins (40–70 kDa, pI 5–8.5) can be identified via two-dimensional gel electrophoresis.
They are classified into two groups: type I (acidic) and type II (basic) polypeptides. Every epithelial cell expresses at least one of each type.
Monoclonal antibodies to cytokeratin proteins serve as useful markers for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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